Cream, gel, ointment or paste preparations formulated to protect the skin from excessive moisture, due to incontinence, perspiration or wound drainage. Indicated for use on Stage I pressure ulcers, on peri-wound skin to prevent maceration, and on pressure points and bony prominences for the prevention of skin breakdown. Ingredients vary based on manufacturers’ formulation but most common skin protectants are dimethicone, petrolatum and zinc oxide. Moisture barriers are often the final step in the process of cleansing, moisturizing and protecting the genital and rectal areas for the prevention of skin breakdown.