Temple University School of Podiatric Medicine

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Wound Care Journal Club Review
March 29th, 2018

Evolving negative pressure wound therapy (NPWT) technology including instillation therapy, nanocrystalline adjuncts, and portable systems can further improve results if used with correct indications. In diabetic foot management, NPWT has had a significant impact on limb salvage. However, it is...

Wound Care Journal Club Review
March 8th, 2018

Diabetes mellitus is frequently associated with chronic non-healing wounds, many of which result in amputation. The combination of peripheral vascular disease, neuropathy, and impaired immune function contributes to a higher risk of injury and deficiency in healing. Wound healing is a complex...

Wound Care Journal Club Review
February 22nd, 2018

An important factor in wound healing is adequate blood flow; thus patients with critical limb ischemia (CLI) and complex wounds are poor healers. Primary treatment for CLI is revascularization. Wound healing can be prolonged as a consequence of cyclical protease production by necrotic tissue...

Wound Care Journal Club Review
January 18th, 2018

A major concern in managing patients with diabetes is their susceptibility to acquiring ulcers in their feet. If these patients are not careful, these ulcers may become infected and eventually lead to additional sequelae, ending in lower extremity amputation. The focus of this study was to...

January 4th, 2018

Staphylococcus aureus is a primary cause of post-operative surgical site infection. S. aureus produces hyaluronidase, which degrades hyaluronic acid (HA). HA is important in wound healing because it prevents bacterial proliferation and provides anti-inflammatory properties....

Wound Care Journal Club Review
December 14th, 2017

Within the last decade, the rise of diabetes in the U.S. population has been matched with a rise in diabetic foot ulcers requiring amputations. Because many of these diabetic foot ulcers develop secondary to poor wound healing and susceptibility to infection after surgery, some important risk...

Wound Care Journal Club Review
December 12th, 2017

Twenty-five percent of all diabetic patients will develop a diabetic foot ulcer (DFU), the major reason for hospitalizations in diabetic patients. The current standard of care (SOC) for DFUs consists of debridement, glycemic control, antimicrobial therapy, and imaging. DFUs often become infected...

Wound Care Journal Club Review
November 30th, 2017

Temple University School of Podiatric Medicine Journal Review Club
Editor's note: This post is part of the Temple...

October 4th, 2017

Wounds with exposed bone and tendon are a major concern for physicians due to the significant morbidity that they can cause. The primary focus of this study is to determine the efficacy and safety of a biologically active, cryopreserved human skin allograft for the treatment of wounds of this...

Wound Care Journal Club Review
September 19th, 2017

Wounds tend to follow a certain algorithm when healing, which can be summed down to three distinct phases: hemostasic/inflammatory, proliferative, and remodeling. Chronic wounds are characterized as wounds that do not follow this pattern and fail to heal within 8 weeks. They tend to occur in...

Wound Care Journal Club Review
September 6th, 2017

One fourth of the approximately 22.3 million patients with diabetes in the United States are expected to develop a diabetic foot ulcer (DFU) at some point during their lives, and it is estimated to affect 1-8% of diabetics annually. DFUs have shown to be challenging to treat, and often result in...

Wound Care Journal Club Review
August 17th, 2017

Chronic wounds and ulcerations induced by complications associated with diabetes mellitus have proven to be a burden to the patients themselves, as well as the healthcare system as a whole. This burden has required physicians to not only find interventions that work better, but are also more...

literature review
March 31st, 2017

Chronic wounds are clinically defined as wounds that have failed to proceed through a healing process in a timely and biologically efficient manner. They are easily identified due to their presence of a raised, hyperproliferative, and non-advancing wound margin. They often are not responsive to...

literature review
March 28th, 2017

Temple University School of Podiatric Medicine Journal Review Club

Keloids are fibrous lesions made of collagen types I and III that arise from an area of wound healing, outside the margins of the original wound and are an unfortunate consequence of irregular wound...

literature review
March 27th, 2017

Diabetic foot ulcers often present in patients with diabetes mellitus, and are a serious and challenging complication that often requires time and costly procedures to treat. Diabetic foot ulcers are very difficult to heal and often become chronic, which increases the incidence of progressing to...

wound care journal club
March 23rd, 2017

Wound healing occurs in four phases: hemostasis, inflammation, tissue growth, and tissue remodeling. The process of wound healing can be affected by multiple factors, including oxygenation, age, stress, and disease such as diabetes. Wound healing in patients with diabetes can be further...

wound care journal club
March 16th, 2017

Venous leg ulcers (VLUs) affect 3% of all people aged 65 years and older. After healing, the recurrence rate can be as high as 69%, making the treatment of VLUs costly to the healthcare system. In Australia alone, VLUs cost the healthcare system $400-500 million per year. VLUs are problematic...

wound care journal club
January 5th, 2017

While opioids are routinely prescribed for painful and chronic wounds, the effects of the medications are not well described in literature. Past studies suggest that stimulation of mu-opiate receptors on keratinocytes may induce transforming growth factor-beta (TGF-beta) and cytokeratin 16 (CK16...

December 8th, 2016

Temple University School of Podiatric Medicine Journal Review Club
Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

wound care journal club
July 27th, 2016

Temple University School of Podiatric Medicine Journal Review Club
Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

WoundSource journal club blog
July 15th, 2016

Temple University School of Podiatric Medicine Journal Review Club
Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

wound care literature review club
June 30th, 2016

Temple University School of Podiatric Medicine Journal Review Club
Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

chicken egg use in wound healing
June 15th, 2016

Temple University School of Podiatric Medicine Journal Review Club
Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

May 20th, 2016

Temple University School of Podiatric Medicine Journal Review Club
Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

wound care journal club
May 5th, 2016

Temple University School of Podiatric Medicine Journal Review Club
Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

wound care journal club
April 21st, 2016

Temple University School of Podiatric Medicine Journal Review Club
Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

Wound Care Literature Review
January 7th, 2016

Temple University School of Podiatric Medicine Journal Review Club
Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

Wound Care Literature Review
December 16th, 2015

Temple University School of Podiatric Medicine Journal Review Club

Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

December 3rd, 2015

Temple University School of Podiatric Medicine Journal Review Club

Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

Wound Care Literature Review
November 19th, 2015

Temple University School of Podiatric Medicine Journal Review Club

Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

Journal Club Review
October 28th, 2015

Temple University School of Podiatric Medicine Journal Review Club

Editor's note: This post is part of the Temple University School of Podiatric Medicine (TUSPM) journal review club blog series. In each blog post, a TUSPM student will review a journal article relevant...

Journal Club Review
October 13th, 2015

Temple University School of Podiatric Medicine Journal Review Club

Article title: Treatment with LL-37 is safe and effective in enhancing healing of hard-to-heal venous leg ulcers: a randomized placebo controlled clinical trial.
Authors:...

Vashe Wound Solution
April 2nd, 2015

by Keval Parikh and James McGuire DPM, PT, CPed, FAPWHc

An important aspect of the field of wound care is the proper preparation of the wound bed. Key points in wound bed preparation include minimizing exudate, assistance in the facilitation of the body’s healing process, and...

March 12th, 2015

by Tasneem Masqati and James McGuire DPM, PT, CPed, FAPWHc

The majority of the wounds of the lower extremity are of arterial, venous or neurotrophic (diabetic) origin. Pressure ulcers are less common on the foot and ankle, however when present on the heel they are a particularly...

Bloodstop iX
February 25th, 2015

by Emily Keeter and James McGuire DPM, PT, CPed, FAPWHc

BloodSTOP™ iX is an absorbable, bioresorbable, lipophilic, animal-free hemostat, which resembles and is designed to handle like gauze. BloodSTOP iX is composed of etherized oxidized regenerated cellulose, which allows it to...

Remedy Products by Medline
February 5th, 2015

by Cerise Adams and James McGuire DPM, PT, CPed, FAPWHc

Our skin is the largest organ in our body requiring a significant amount of vascular support to stay healthy and protective. As we get older, our circulation slows down just when our skin needs more support and more...

December 24th, 2014

by Evangelia Athanasoula and James McGuire DPM, PT, CPed, FAPWHc

The sorbion sachet wound dressing, manufactured by sorbion GmbH & Co. in Germany and marketed in the US by Alliqua Biomedical, is a high capacity dressing that absorbs and holds wound exudate, removes some wound...

December 18th, 2014

by Rizwan Tai and James McGuire DPM, PT, CPed, FAPWHc

According to Centers for Disease Control and Prevention (CDC), the number of adults between the ages of 18-79 with newly diagnosed diabetes has more than tripled in the last 30 years. Foot ulcers are a major complication of...

December 2nd, 2014

by Tedman L. Tan and James McGuire DPM, PT, CPed, FAPWHc

The management of diabetic foot ulcers is becoming an increasingly significant concern with the growing population of patients...

gauze
November 20th, 2014

by Keval Parikh and James McGuire DPM, PT, CPed, FAPWHc

There are many different kinds of wound dressings available. Choosing one to use depends on the unique characteristics of the wound. According to Watson and...

marathon liquid skin protectant
October 23rd, 2014

by Peter Smith and James McGuire DPM, PT, CPed, FAPWHc

Marathon® Liquid Skin Protectant by Medline Industries, Inc. is a versatile non-stinging barrier film that provides protection for at-risk skin...

October 8th, 2014

by Chinenye Queen Ezike and James McGuire DPM, PT, CPed, FAPWHc

Venous Leg Ulcers (VLUs) are the most common cause of lower extremity ulcerations, affecting about 1% of the US population1. Recurrence rates for VLUs are...

October 1st, 2014

by Carmelita Harbeson and James McGuire DPM, PT, CPed, FAPWHc

Hemostasis, the resolution of bleeding, consists of several intricate and controlled steps: platelet activation, coagulation, and vascular repair1. Whether bleeding is caused by surgery, trauma, or wound debridement,...

September 24th, 2014

By Bradley W. Lind and James McGuire DPM, PT, CPed, FAPWHc

Venous leg ulcers are a type of lower extremity wound complicated by excess fluid production, periwound edema, and high bioload produced by venous insufficiency often leading to secondary lymphedema. The...

August 27th, 2014

by Elliot Fialkoff and James McGuire DPM, PT, CPed, FAPWHc

There are numerous causes for ulcerations including pressure, venous insufficiency, arterial insufficiency, and neuropathic wounds. All have very different characteristics and require very different interventions. One...

August 18th, 2014

by Sejal Bhojani and James McGuire DPM, PT, CPed, FAPWHc

RTD® (Retro-Tech Dressing) is a foam wound dressing that has been designed to promote healing in chronic wounds by utilizing...

August 1st, 2014

by Elliot Fialkoff and James McGuire DPM, PT, CPed, FAPWHc

Ulcers, wounds, and burns come in many different shapes and sizes based in part on their etiology, which also varies dramatically. As many different etiologies as there are for various dermatological insults, there is an...

July 18th, 2014

by Carmelita Harbeson and James McGuire DPM, PT, CPed, FAPWHc

Compression therapies work to restore circulation, reduce edema, and enhance tissue stability. With the myriad of compression options available, sorting through which treatments are best for each patient can be a...

July 10th, 2014

by Brittany Charmaine Sumpter and James McGuire DPM, PT, CPed, FAPWHc

Drawtex™ wound dressings utilize a hydroconductive material to aid the clinician in wound bed preparation. It is a highly absorbent wound...

July 3rd, 2014

by James McGuire, DPM, PT, CPed, FAPWHc

The world of wound care is getting more complicated by the day. New products emerge almost weekly and further confuse the practitioner who is bombarded with ads and weekly visits from company representatives who tout the benefits of their...