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Helicoll® is a bioengineered high purity type I collagen membrane. Acellular bioactive skin substitute is bioresorbable to facilitate tissue regeneration for wound management. Flexible and translucent with moderate tackiness.

EnColl Corporation

EnColl Corporation is a California corporation that develops, manufactures and markets type I collagen-based products.

• Granulation in four to five days
• Helps reduce pain
• Rehydrates in saline solution in five minutes
• Can be used with negative pressure wound therapy
• Priced to be used inpatient as well as outpatient
• Collagen fibrils are organized in a parallel pattern similar to that of native tissue fibrillar structure
• Porosity is approximately 20μ to attract more cells/regenerative factors
• Patented process yields high purity type-I bovine collagen (>97% homologous to human type I collagen) allowing for biocompatibility


Helicoll® is indicated for use on diabetic ulcers, pressure injuries, venous ulcers, draining wounds with slit openings, partial- or full-thickness wounds, tunneling or undermined wounds, surgical wounds (i.e., donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric or wound dehiscence) and trauma wounds (i.e., abrasions, lacerations, second-degree burns or skin tears).

Storage Requirements

3 year shelf life at room temperature

Active Ingredients

Bovine type-I collagen

How Supplied/Sizing
25sq cm, 50sq cm, 100sq cm, 400sq cm.
Product features
check_circle Assigned HCPCS code
cancel Minimally manipulated
cancel Dehydrated
cancel Desiccated
cancel Flowable
cancel Micronized
check_circle Sheet form
cancel Requires refrigeration
check_circle Shelf life greater than 2 years
cancel Shelf life limited
check_circle Indicated for acute wounds
check_circle Indicated for chronic wounds
check_circle Indicated for diabetic ulcers
check_circle Indicated for pressure ulcers
check_circle Indicated for second-degree burns
check_circle Indicated for surgical wounds
cancel Indicated for third-degree burns
check_circle Indicated for venous ulcers
cancel Contact manufacturer for usage guidelines
Other features
check_circle Educational Material Available
cancel Free Samples/Trials Available
check_circle Published Clinical Article Available
Recommended Use

Acute Wounds
Chronic Wounds
Deep Wounds Wounds
Dehisced Wounds
Diabetic Foot
Granulating/Epitheliasing Wounds
Hypertrophic Scars/Keloids
Infected Wounds
Moderate/Highly Exudating Wounds
Non/Minimally Exudating Wounds
Palliative Wounds
Pressure Ulcers
Sloughy Wounds
Superficial Wounds
Surgical Wounds
Venous Ulcers

Mode of Use/Application

Remove Helicoll® from package and separate first the clear polymer sheet. Soak in sterile saline for approximately for five to ten minutes and remove the other white polymer sheet also. Apply Helicoll® over the debrided wound bed and remove any trapped air bubbles. In surgical settings, Helicoll® can be retained in place using tape, suture or staples. Refer to the Helicoll® application guide to apply a non-adherent porous dressing sheet over Helicoll® and for the secondary compressive dressing applications. Leave Helicoll® in place for five to seven days, unless any complication or infection arises. Prophylactic antibiotic may be used as the doctor prefers. Helicoll® will absorb into the wound bed. Make slits with a surgical scalpel if needed when exudate is present.

Removal & Change Frequency

Removal of a Helicoll® membrane is not required except when wound is infected or if excessive exudate is under the Helicoll® membrane. For slowly healing chronic wounds, it may be changed after five to seven days.

Additional Recommended Dressings

Apply every 7 days as needed.

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