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Matrix™ HD

Matrix™ HD is an acellular human dermis graft that is provided sterile with room temperature storage and a five year shelf life. Matrix™ HD is available in standard and pre-fenestrated configurations.

RTI Surgical, Inc.

RTI Surgical is a leading global surgical implant company providing safe biologic, metal and synthetic implants. RTI's implants are used in sports medicine, general surgery, spine, trauma, orthopedic and cardiothoracic procedures and are distributed in over 50 countries.
Toll free:(877) 343-6832 Fax:(386) 418-0342 Website:

• Sterilized using the Tutoplast® process
• Validated viral inactive
• Sterility Assurrance Level 10-6
• Retains the original three-dimensional collagen structure responsible for the multi-directional, mechanical properties of dermal tissue
• Revascularization evident in as early as seven days
• Single step rehydration


Matrix™ HD is cleared for the homologous use of protection, reinforcement, or covering of soft tissue to provide a natural collagen scaffold that supports the body's regenerative processes. Matrix™ HD does not have limited indications per wound type or condition.

Warnings and Precautions

The Matrix™ HD implant should be used with caution in surgical sites where an active infection is present or in sites with poor perfusion. The implant should be used with caution in surgical procedures where it is under moderate to high tension.

Storage Requirements

Storage at room temperature for up to five years.

How Supplied/Sizing
Standard: 2cmx2cm, 2cmx14cm, 4cmx5cm, 5cmx8cm, 10cmx10cm, 13cmx15cm. Fenestrated: 4cmx5cm, 5cmx8cm.
Product features
check_circle Assigned HCPCS code
cancel Minimally manipulated
cancel Cryopreserved
cancel Dehydrated
cancel Desiccated
cancel Flowable
cancel Micronized
check_circle Sheet form
cancel Requires refrigeration
check_circle Shelf life greater than 2 years
cancel Shelf life limited
cancel Indicated for acute wounds
cancel Indicated for chronic wounds
cancel Indicated for diabetic ulcers
cancel Indicated for pressure ulcers
cancel Indicated for surgical wounds
cancel Indicated for third-degree burns
cancel Indicated for venous ulcers
check_circle Contact manufacturer for usage guidelines
Recommended Use

Acute Wounds
Arterial Ulcers
Chronic Wounds
Deep Wounds
Dehisced Wounds
Diabetic Foot
Granulating/Epithelializing Wounds
Moderate/Highly Exudating Wounds
Non/Minimally Exudating Wounds
Pressure Ulcers
Superficial Wounds
Surgical Wounds
Venous Ulcers

Mode of Use/Application

Prepare and debride the wound bed per standard protocol. Rehdrate the The Matrix™ HD graft in room temperature sterile saline or water. Other rehydration methods such as blood and platelet-rich plasma (PRP) have also been used.

Size and trim the graft according to the tissue defect, leaving an excess border for fixation. Some physicians may prefer to apply the graft with the reticular side in contact with the wound bed and the basement membrane facing out. The reticular side has a rough, dull appearance the basement membrane has a smooth, shiny appearance.

Use preferred fixation method to secure the graft to the wound bed. The graft must be securely placed to prevent displacement and to aid in incorporation to the wound bed. Some common fixation methods include sutures, staples, or steri-strips.

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