Acute Wounds
Chronic Wounds
Deep Wounds
Diabetic Foot
Necrotizing Fasciitis
Pressure Ulcers
Venous Ulcers

Prepare the wound using standard methods ensuring that the wound is free of debris and devitalized tissue. An initial debridement of the wound may be necessary to ensure the wound edges contain viable tissue. Using aseptic technique, manually or with forceps, place the product directly in contact with the wound surface. Miro3D® Fibers should be placed in maximum possible contact with healthy, well-vascularized tissue as a scaffold which provides a protective environment for the wound. If choosing to apply the product dry, it may be hydrated in situ with sterile saline or lactated Ringer’s solution. Use an appropriate non-adherent primary wound dressing over Miro3D® Fibers to prevent it from adhering to the dressing and to protect the integrity of the applied product and not disrupt the wound site. Apply an appropriate secondary dressing that will manage the wound exudate, keep Miro3D® Fibers moist, and keep all layers securely in place. Discard any unused portion of the Miro3D® Fibers product and the package in accordance with accepted medical practice and applicable local, state, and federal laws and regulations. As healing occurs, sections of Miro3D® Fibers may not integrate. Carefully remove any remaining loose product as needed. Do not remove any remaining Miro3D® Fibers that has integrated. If the wound is free of infection and necrosis but not fully epithelialized, follow standard clinical protocol for additional application or therapy.

As healing occurs, sections of Miro3D® Fibers Wound Matrix may gradually peel. Carefully remove any remaining loose product around the edge as needed. Do not remove any remaining Miro3D® Wound Matrix that has integrated. If the wound is free of infection and necrosis but not fully epithelialized, follow standard clinical protocol for additional application or therapy.

Reprise Biomedical, Inc. warrants that Miro3D® Fibers is free from defects in workmanship and materials prior to the stated expiration date. Liability under this warranty is limited to refund or replacement of any product, which has been found by Reprise Biomedical to be defective in workmanship or materials. Reprise Biomedical shall not be liable for an incidental, special, or consequential damage arising from the use of Miro3D® Fibers. Damage to the product through misuse, alteration, improper storage, or improper handling shall void this limited warranty. No employee, agent, or distributor of Reprise Biomedical has any authority to alter or amend this limited warranty in any respect. Any purported alteration or amendment shall not be enforceable against Reprise Biomedical. THIS WARRANTY IS EXPRESSLY IN LIEU OF ALL OTHER WARRANTIES, EXPRESSED OR IMPLIED, INCLUDING ANY WARRANTY OF MERCHANTABILITY OR FITNESS FOR PARTICULAR PURPOSE OR ANY OBLIGATION OF REPRISE BIOMEDICAL.