Debridement and Wound Care: Important Terms to Know Protection Status
Blog Category: 

Collagenase: An enzymes that breaks the peptide bonds in collagen. Collagenases aid in destroying extracellular structures. Collagenase is one of the most frequently used enzymatic debridement agents.

Enzymatic debridement: A topical treatment that uses naturally occurring proteolytic enzymes or proteinases, which break down and remove devitalized tissue by digesting and dissolving this tissue in the wound bed.

Keratotic tissue: Keratotic tissue is the development of horny growths (keratomas). These growths can appear at the edges of wounds and hinder healing. They are removed by debridement to promote healing.

How much do you know about debridement and chronic wounds? Take our 10-question quiz to find out! Click here.

Limb salvage program: A standard of care to address patients at risk of amputation. Limb salvage strategies include early detection, treatment, and prevention of diabetic foot ulcers.

Liquefactive necrosis: The death of tissue in which a yellow liquid layer accumulates, consisting of dead leukocytes. This type of necrosis is generally caused by bacterial, viral, parasitic, or fungal infections.

Matrix metalloproteinases (MMPs): A group of enzymes that break down the extracellular matrix and delay healing. They are often found in excessive amounts in chronic wounds.

Offloading: Offloading is minimizing and removing weight placed on the surface such as the plantar foot or over a bony prominence such as the elbow to help prevent and heal wounds. This can be performed through means such as bed rest, crutches, wheelchairs, scooters, walkers, casts, splints, offloading wedges, and specialty shoes.

Proteinase: Proteinase may also be referred to as peptide or protease. Proteinases are enzymes that catalyze proteolysis, or the breakdown of proteins into smaller polypeptides or single amino acids.

Slough: Devitalized tissue containing white blood cells and wound debris. It can appear yellow or white, soft or leathery, and thick or thin. Slough must be removed to facilitate healing.

Surgical/sharp debridement: The removal of devitalized tissue by a skilled clinical practitioner using surgical instruments, such as a scalpel or curette. Sharp debridement is often the preferred method in treating diabetic foot ulcers.

May is Debridement and Chronic Wounds Month

The views and opinions expressed in this blog are solely those of the author, and do not represent the views of WoundSource, Kestrel Health Information, Inc., its affiliates, or subsidiary companies

Recommended for You

  • June 30th, 2021

    Wound bed maintenance is the process taken by the bedside clinician or nurse to create or preserve the wound environment at optimal conditions and thus encourage the chronic wound to move to a state of closure or healing. Critical thinking skills require a trained eye focused on the...

  • June 30th, 2021

    Wound bed preparation has been performed for decades in managing wounds of various etiologies. The wound healing process consists of a complex interlinked and independent cascade, which not all wounds follow in a consistent, organized manner. The TIMERS acronym, consisting of four general steps...

  • February 28th, 2021

    Chronic and non-healing wounds are those that do not progress through the healing process in a timely or predicted manner. They are a global problem and are becoming harder to treat. Medicare estimates that over 8 million Americans have chronic wounds that cost the national health care system...

Important Notice: The contents of the website such as text, graphics, images, and other materials contained on the website ("Content") are for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. The content is not intended to substitute manufacturer instructions. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or product usage. Refer to the Legal Notice for express terms of use.