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AmnioWrap2™ is a placenta-based allograft comprised of unseparated amnion and chorion membranes including the intact intermediate layer. The allograft contains collagen extracellular matrix and a wide array of regulatory proteins including growth factors, cytokines, and chemokines.

Direct Biologics, LLC

Direct Biologics is a market-leading innovator and cGMP manufacturer of regenerative medical products, including a line of extracellular vesicle-based biological products.
Fax:(800) 791-1841 Website:

• Contains hyaluronic acid (HA) + collagen
• Contains growth factors
• Contains glycosaminoglycans and proteoglycans


AmnioWrap2™ has been used by clinicians in the following applications: wounds, burns, aesthetic applications, soft tissue injuries, over tendons, and ligaments.


The presence of severe vascular compromise, active or latent infection, or uncontrolled infection at the site may compromise the usefulness of the allograft.

Warnings and Precautions

This allograft must not be used under any of the following circumstances:
• If the container seal is damaged or not intact or has any physical damage
• If the container label is severely damaged, illegible, or missing
• If the expiration date shown on the container label has passed

Storage Requirements

AmnioWrap2™ is packaged dry and stored at ambient temperature. AmnioWrap2™ has a three-year shelf life.

How Supplied/Sizing
1cmx1cm, 2cmx2cm, 2cmx3cm, 3cmx3cm.
Product features
check_circle Assigned HCPCS code
cancel Minimally manipulated
cancel Cryopreserved
check_circle Dehydrated
check_circle Desiccated
cancel Flowable
cancel Micronized
check_circle Sheet form
cancel Requires refrigeration
check_circle Shelf life greater than 2 years
cancel Shelf life limited
cancel Indicated for acute wounds
cancel Indicated for chronic wounds
cancel Indicated for diabetic ulcers
cancel Indicated for pressure ulcers
cancel Indicated for surgical wounds
cancel Indicated for third-degree burns
cancel Indicated for venous ulcers
check_circle Contact manufacturer for usage guidelines
Other features
check_circle Educational Material Available
check_circle Free Samples/Trials Available
cancel Published Clinical Article Available
Recommended Use

Acute Wounds
Cavity Wounds
Chronic Wounds
Deep Wounds
Dehisced Wounds
Diabetic Foot
Granulating/Epithelializing Wounds
Hypertrophic Scars/Keloids
Moderate/Highly Exudating Wounds
Non/Minimally Exudating Wounds
Palliative Wounds
Pressure Ulcers
Superficial Wounds
Surgical Wounds
Traumatic Wounds
Venous Ulcers

Mode of Use/Application

Remove the graft from the pouch and apply directly onto the area of treatment.

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