Helicoll® is a bioengineered high purity type I collagen (>97% pure) skin substitute that is highly bioactive, cell conducive, and supportive towards enhancing tissue generation for wound management.
• Patented reconstituted bioactive collagen sheet, free of immunogenic proteins, lipids, and elastin
• Native structure of the collagen is not altered or cross-linked which maintains its high bioactivity
• Collagen phosphorylation attracts cells, regenerates tissue, and stimulates blood capillaries/granulation within 4 to 5 days
• No washing needed prior to use
• Can be cut, sutured, or stapled
• Effectively reduces pain
• Choose from standard or customized dimensions
• Accelerated wound healing and tissue remodeling with minimal applications reduce the treatment cost by over 40%
• Remains clinically usable for 3 years when stored in room temperature conditions
Helicoll offers significant advantages over traditional collagen products derived from routine extraction procedures resulting with lesser purity and biocompatibility. Helicoll ensures the presence of only high-purity Type-I collagen through its US patented process.
Only Type-I collagen is proven to have the maximum homology with the Type-I collagen of other species, either allograft or xenograft. Type-I Collagen does not cause an immunogenic response due to its lack of sulfur-containing amino acid cysteine.
Helicoll’s high purity Type-I collagen, a full native molecule and uncross-linked providing 3,000 active receptor sites per molecule for growth factors, ligands and cells like fibroblasts to attach to make it as an excellent matrix for use in wound healing.
In addition to the high biocompatibility, the unique feature of Helicoll’s Type-I collagen is its post-translational modification called phosphorylation. This add-on feature makes the matrix highly bioactive through cell signal transduction phenomenon. It has been proven clinically by the infiltration of new blood capillaries (neo-vascularization) within 4 to 5 days after application resulting in faster wound healing and tissue regeneration.
Overall, Helicoll's purified, phosphorylated Type-I collagen offers superior biocompatibility and functionality, making it an excellent choice for biomedical and research applications, particularly in tissue regeneration and wound healing.
Helicoll® is indicated for use on partial- and full-thickness wounds, pressure ulcers, venous ulcers, chronic vascular ulcers, diabetic ulcer, trauma wounds (i.e., abrasions, lacerations, skin tears, second-degree burns), surgical wounds (ie, donor sites/grafts, post–Mohs surgery, post-laser surgery, podiatric or wound dehiscence). Helicoll is FDA 510(k) cleared.
Helicoll® is derived from a bovine or ovine source and should not be used in patients with known sensitivity to such material. This device is not indicated for third-degree burns.
Do not resterilize. Helicoll® is sterile if the package is dry, unopened and undamaged. Do not use if the
package seal is broken. The device must be used prior to the expiration date. Discard all open Helicoll®
and any unused portions. Helicoll® is available by medical prescription only.
3 year shelf life at room temperature
Bovine type-I collagen
Acute Wounds
Chronic Wounds
Deep Wounds Wounds
Dehisced Wounds
Diabetic Foot
Granulating/Epitheliasing Wounds
Hypertrophic Scars/Keloids
Infected Wounds
Moderate/Highly Exudating Wounds
Non/Minimally Exudating Wounds
Palliative Wounds
Pressure Ulcers
Sloughy Wounds
Superficial Wounds
Surgical Wounds
Venous Ulcers
Remove Helicoll® from package and separate first the clear polymer sheet. Soak in sterile saline for approximately for five to ten minutes and remove the other white polymer sheet also. Apply Helicoll® over the debrided wound bed and remove any trapped air bubbles. In surgical settings, Helicoll® can be retained in place using tape, suture or staples. Refer to the Helicoll® application guide to apply a non-adherent porous dressing sheet over Helicoll® and for the secondary compressive dressing applications. Leave Helicoll® in place for five to seven days, unless any complication or infection arises. Prophylactic antibiotic may be used as the doctor prefers. Helicoll® will absorb into the wound bed. Make slits with a surgical scalpel if needed when exudate is present.
Removal of a Helicoll® membrane is not required except when wound is infected or if excessive exudate is under the Helicoll® membrane. For slowly healing chronic wounds, it may be changed after five to seven days.
Apply every 7 days as needed.
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