Integra® PriMatrix® Ag Antimicrobial Dermal Repair Scaffold

• Contains ionic silver to inhibit microbial colonization of the matrix
• Antimicrobial content - ionic silver; average per unit content up to 165 micrograms/sq cm
• Acellular collagen matrix derived from fetal bovine dermis
• Rich in type III collagen, a collagen that is active in developing and healing tissues
• Superior handling characteristics
• 34 month shelf life
• Room temperature storage
• Minimal preparation time – rehydrates in about 60 seconds
• Biocompatible and cell-friendly with no artificial chemical crosslinking
• Terminally sterilized
• No detrimental foreign body inflammatory response

Integra® PriMatrix® Ag Antimicrobial Dermal Repair Scaffold is intended for the management of wounds that include: partial- and full-thickness wounds; pressure, diabetic and venous ulcers; second-degree burns; surgical wounds including donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric, wound dehiscence; trauma wounds including abrasions, lacerations and skin tears; tunneled/undermined wounds; draining wounds.

Integra® PriMatrix® Ag Antimicrobial Dermal Repair Scaffold should not be used for patients with a known history of hypersensitivity to silver, collagen or bovine products.

Silver-containing compounds are known to cause a condition known as argyria, a silver-induced darkening of the skin. Frequent or prolonged use of Integra® PriMatrix® Ag Antimicrobial Dermal Repair Scaffold may result in skin discoloration.

The following complications are possible. If any of these conditions occur, the device should be removed.
• Infection
• Chronic inflammation
• Allergic reaction
• Excessive redness, pain, swelling or blistering