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Integra® Wound Matrix

Integra® Wound Matrix is an advanced wound care device consisting of a porous, three-dimensional dermal layer comprised of collagen and glycosaminoglycan. The dermal layer is designed with a controlled porosity and defined degradation rate that provides a scaffold for cellular invasion and capillary growth.

Integra LifeSciences Corp.

Integra LifeSciences, a world leader in medical technology, is dedicated to limiting uncertainty for surgeons so they can concentrate on providing the best patient care. Integra offers innovative solutions in orthopedic extremity surgery, neurosurgery and reconstructive and general surgery.
Toll free:(800) 654-2873 Fax:(888) 980-7742 Website:

• Provides immediate wound coverage
• Highly conformable for various anatomic sites
• Provides a scaffold for cellular invasion and capillary growth
• Room temperature storage


Integra® Wound Matrix is indicated for the management of wounds including: partial- and full-thickness wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, surgical wounds (donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric, wound dehiscence), trauma wounds (abrasions, lacerations, second-degree burns and skin tears) and draining wounds. The device is intended for one-time use.


This device should not be used in patients with known sensitivity to bovine collagen or chondroitin materials. This device is not indicated for use in third-degree burns.

Warnings and Precautions

Do not resterilize. Discard all opened and unused portions of the device. Do not use if package seal is broken.

Adverse Effects/Reactions

Complications are possible with the use of wound dressings including infection, chronic inflammation, allergic reaction, excessive redness, pain or swelling.

Storage Requirements

Room temperature with a 24-month shelf life.

How Supplied/Sizing
2"x2", 4"x5", 4"x10", 8"x10".
Product features
check_circle Assigned HCPCS code
cancel Minimally manipulated
cancel Dehydrated
cancel Desiccated
cancel Flowable
cancel Micronized
check_circle Sheet form
cancel Requires refrigeration
cancel Shelf life greater than 2 years
check_circle Shelf life limited
check_circle Indicated for acute wounds
check_circle Indicated for chronic wounds
check_circle Indicated for diabetic ulcers
check_circle Indicated for pressure ulcers
cancel Indicated for second-degree burns
check_circle Indicated for surgical wounds
cancel Indicated for third-degree burns
check_circle Indicated for venous ulcers
cancel Contact manufacturer for usage guidelines
Other features
check_circle Educational Material Available
cancel Free Samples/Trials Available
cancel Published Clinical Article Available
Recommended Use

Acute Wounds
Chronic Wounds
Deep Wounds
Diabetic Foot
Hypertrophic Scars/Keloids
Pressure Ulcers
Surgical Wounds
Venous Ulcers

Mode of Use/Application

Using aseptic technique, peel open the outer pouch and gently drop the inner foil pouch onto a sterile field or surface. Using sterile technique, place foil pouch flat and peel open the inner pouch. Remove product, including the protective polyethylene sheets. Separate product from the polyethylene sheets by slowly and carefully peeling back from one of the corner edges. Handle with care as product is fragile. Place product into basin containing a sterile saline solution. Rinse the product free of storage buffer by immersion in sterile saline for one to two minutes. Keep product in the basin until application.

Prepare wound bed using standard methods to ensure wound is free of debris and necrotic tissue. If necessary, surgically debride the wound to ensure the wound edges contain viable tissue. Cut the device to size and apply immediately following wound bed preparation. Smooth Integra® Wound Matrix into place to ensure sheet is in contact with the underlying wound bed.

After application, use appropriate secondary dressings to maintain device adherence and protect the wound area. The optimum secondary dressing is determined by wound location, size, depth and user preference.

Additional Recommended Dressings

Change the secondary dressings as needed. Frequency of secondary dressing change will be dependent upon volume of exudate produced, type of dressing used and the clinician's need to inspect the wound bed for signs of infection or healing.

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