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Kerecis® Omega3 MariGen

Kerecis® Omega3 MariGen is a fish-skin graft that is homologous to human skin and is used for tissue regeneration. The fish skin is a natural microbial barrier.

Kerecis, LLC

Kerecis is pioneering the use of fish skin and fatty acids for tissue regeneration, with the mission to extend life by supporting the body's own ability to regenerate.
Fax:(703) 918-4847 Website:

• Homologous to human skin and rich in Omega3
• Two non-industry funded, double-blind RCTs
• Faster healing than amnion membrane and mammalian tissue
• Superior economic performance
• Natural microbial barrier
• Sustainably harvested


Kerecis® Omega3 MariGen is indicated for partial- and full-thickness wounds, pressure injuries, venous ulcers, chronic vascular ulcers, diabetic ulcers, trauma wounds (abrasions, lacerations, second-degree burns, skin tears), surgical wounds (donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric, wound dehiscence), and draining wounds.


Contraindicated for use on patients with a known allergy or other sensitivity to fish material.

Warnings and Precautions

Remove most of the necrotic tissue prior to device application.
Remove exudate and control bleeding prior to device application.
Do not reuse or re-sterilize.
Discard unused portions of device.
Sterile if package is unopened and undamaged.
Do not use device if package seal has been broken or if handling has caused damage or contamination.
Do not use in case of known fish allergies.

Storage Requirements

Store at or below 25°C (no more than 40°C), away from direct sunlight. Keep dry. For one time use only.

Inactive Ingredients

Intact, decellularized, lyophilized fish skin

How Supplied/Sizing
1(3/4)cmx1(3/4)cm, 3cmx3(1/2)cm, 3cmx7cm, 5cmx7cm, 7cmx7cm, 7cmx10cm. Circular: 16mm. Fenestrated: 3cmx3(1/2)cm, 3cmx7cm, 7cmx10cm. Micro: 4sq cm, 8sq cm, 19sq cm, 38sq cm. Expanse: 7cmx8cm, 8cmx10cm; 2:1 premeshed.
Product features
check_circle Assigned HCPCS code
cancel Minimally manipulated
cancel Dehydrated
cancel Desiccated
cancel Flowable
cancel Micronized
check_circle Sheet form
cancel Requires refrigeration
check_circle Shelf life greater than 2 years
cancel Shelf life limited
check_circle Indicated for acute wounds
check_circle Indicated for chronic wounds
check_circle Indicated for diabetic ulcers
check_circle Indicated for pressure ulcers
check_circle Indicated for second-degree burns
check_circle Indicated for surgical wounds
cancel Indicated for third-degree burns
check_circle Indicated for venous ulcers
cancel Contact manufacturer for usage guidelines
Other features
check_circle Educational Material Available
check_circle Free Samples/Trials Available
check_circle Published Clinical Article Available
Recommended Use

Chronic Vascular Ulcers
Diabetic Ulcers
Draining Wounds
Partial- and Full-Thickness Wounds
Pressure Ulcers
Surgical Wounds
Trauma Wounds
Venous Ulcers

Mode of Use/Application

Always handle Kerecis® Omega3 Marigen in an aseptic manner. When applying Kerecis® Omega3 Marigen for the first time, clean the wound bed by removing necrotic tissue to obtain a fresh tissue surface. Irrigate excessive exudate. Control bleeding. Remove the Kerecis® Omega3 Marigen sheet from the pouch in an aseptic manner. Cut the sheet roughly to the size of the area to be covered and pre-hydrate in NaCl solution. Apply sheet directly to wound, making sure that the sheet does not overlap the wound edges. More than one sheet may be necessary for complete coverage. Overlap sheet edges slightly to assure coverage of the entire wound. Apply an appropriate secondary, non-adherent wound dressing to maintain a moist wound environment.

Additional Recommended Dressings

Non-adherent secondary dressing

Clinically Tested


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