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MicroMatrix® is a sterile, porcine-derived, naturally-occurring lyophilized extracellular matrix in particle form that maintains and supports a healing environment for wound management.

ACell, Inc.

ACell, Inc. offers Cytal™ and MicroMatrix® products that maintain and support a healing environment through constructive remodeling. Indicated for acute and chronic wounds.
Toll free:(800) 826-2926 Fax:(410) 715-4511 Website:

• Supports a healing environment through constructive remodeling
• Comprised of naturally-occurring urinary bladder matrix
• Contains basement membrane and numerous collagens
• Appropriate for acute wounds and chronic wounds
• Maintains an intact epithelial basement membrane
• Non-crosslinked wound management scaffold


MicroMatrix® (particles) are intended for management of topical wounds including: partial- and full-thickness wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunneled/undermined wounds, surgical wounds (donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric, wound dehiscence), trauma wounds (abrasions, lacerations, second-degree burns and skin tears) and draining wounds. The device is intended for one-time use.


Contraindicated for use on patients with known sensitivity or allergy to porcine materials or third-degree burns.

Warnings and Precautions

Do not re-use or re-sterilize. Do not use device if package seal has been broken.

Adverse Effects/Reactions

Complications and reactions are possible with any soft tissue repair, including but not limited to: infection, increased chronic inflammation, allergic reaction, unexplained fever or chills, excessive redness, pain or swelling.

Storage Requirements

Store in a clean, dry environment between 15°C-35°C (59°F-95°F) in unopened and undamaged package.

How Supplied/Sizing
20mg to 1,000mg.
Product features
check_circle Assigned HCPCS code
cancel Minimally manipulated
cancel Dehydrated
cancel Desiccated
cancel Flowable
check_circle Micronized
cancel Sheet form
cancel Requires refrigeration
cancel Shelf life greater than 2 years
cancel Shelf life limited
check_circle Indicated for acute wounds
check_circle Indicated for chronic wounds
check_circle Indicated for diabetic ulcers
check_circle Indicated for pressure ulcers
cancel Indicated for second-degree burns
check_circle Indicated for surgical wounds
cancel Indicated for third-degree burns
check_circle Indicated for venous ulcers
cancel Contact manufacturer for usage guidelines
Other features
check_circle Educational Material Available
check_circle Free Samples/Trials Available
check_circle Published Clinical Article Available
Recommended Use

Chronic Wounds
Diabetic Foot
Pressure Ulcers
Surgical Wounds
Venous Ulcers

Mode of Use/Application

Clean wound according to manufacturer instructions and clinical protocol. Aseptically remove the MicroMatrix® from packaging. Rinse wound with sterile saline. Apply device to wound surface lightly covering the entire wound. Discard any unused portions of device.

Wet wound: Cover MicroMatrix® with non-adherent moist dressing such as petrolatum gauze, followed by application of an absorptive dressing such as a calcium alginate. Secure dressings to wound site.

Dry wound: Cover MicroMatrix® with non-adherent moist dressing followed by application of a hydrogel dressing to keep wound moist. Secure dressings to wound site. Keep dressing and wound bed moist.

Devices are supplied sterile by electron beam irradiation in a vial or container and a peel-open package. Device is sterile if package is unopened and undamaged.

Removal & Change Frequency

Inspect wound for adverse reactions every other day; rinse with sterile saline and apply powder to any non-healed areas. As wound heals, it may form a caramel-colored area over wound surface. Gently rinse wound surface leaving caramel-colored area intact. Apply wound dressings according to manufacturer's application instructions. Repeat wound care follow-up every other day until wound healing occurs.

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