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NuShield® is a sterile and shelf-stable dehydrated placental allograft wound covering that retains all the layers of the placental membrane due to the novel LayerLoc™ preservation method.


Organogenesis is a global leader in advanced wound care, offering a comprehensive portfolio of regenerative medicine products capable of supporting patients from early in the wound healing process through to wound closure, regardless of wound type.
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• Novel LayerLoc™ preservation method retains all layers of the placental membrane that contain numerous growth factors and cytokines
• Real-world evidence demonstrated that Nushield®, used as a protective wound covering, helps support an optimal environment for healing in a variety of wound types and sizes


NuShield® is an allograft intended for use in the management of acute and chronic wounds as well as appropriate surgical applications. NuShield® may be applied as a wound covering to a variety of partial- and full-thickness acute and chronic wounds and wounds with exposed tendon, muscle, joint capsule and bone. NuShield® can be applied from the onset and for the duration of the wound, weekly or at the discretion of the health care practitioner.


NuShield® is contraindicated for use on clinically infected wounds.
NuShield® is contraindicated for surgical implantation sites with active or latent infection.
Please refer to the NuShield® Instructions for Use for more information.

Warnings and Precautions

As with all allogeneic materials, it is not possible to provide an absolute guarantee that no infectious disease will be transmitted. However, this risk is greatly reduced by using processing treatments shown to be capable of reducing this risk as well as the use of strict donor screening criteria, laboratory testing, aseptic processing and terminal gamma irradiation of final product. Single patient, single use only. Do not sterilize or re-sterilize.

Adverse Effects/Reactions

Transmission of diseases of unknown etiology; transmission of known infectious agents including, but not limited to, viruses, bacteria and fungi; immune rejection of implanted HCT/P; or loss of function and/or integrity of implanted HCT/P due to resorption, fragmentation and/or disintegration.

Storage Requirements

Store at ambient temperature.

How Supplied/Sizing
2cmx3cm, 2cmx4cm, 3cmx4cm, 3.2cmx3.2cm, 4cmx4cm, 4cmx6cm, 6cmx6cm. Disk: 1.6cm.
Product features
check_circle Assigned HCPCS code
check_circle Minimally manipulated
cancel Cryopreserved
check_circle Dehydrated
cancel Desiccated
cancel Flowable
cancel Micronized
check_circle Sheet form
cancel Requires refrigeration
check_circle Shelf life greater than 2 years
cancel Shelf life limited
check_circle Indicated for acute wounds
check_circle Indicated for chronic wounds
check_circle Indicated for diabetic ulcers
check_circle Indicated for pressure ulcers
check_circle Indicated for surgical wounds
cancel Indicated for third-degree burns
check_circle Indicated for venous ulcers
check_circle Contact manufacturer for usage guidelines
Other features
check_circle Educational Material Available
check_circle Free Samples/Trials Available
check_circle Published Clinical Article Available
Mode of Use/Application

Remove NuShield® from its sterile packaging using aseptic technique, being careful to maintain the sterility of the product. To determine which side of NuShield® is the chorion side (to be placed in contact with the wound bed), verify that the middle notch is at the top, and the notched corner is to its right, then the upper side is epithelial and the side facing down is chorion. Place NuShield® onto the wound bed, being careful to preserve orientation of the product and ensure that the chorion side is in contact with the wound bed. Once NuShield® is placed, the product may be rehydrated as necessary, based on the characteristics of the wound (NuShield® is easier to handle prior to rehydration).

Additional Recommended Dressings

A non-adherent, non-occlusive primary dressing may be used directly over NuShield®.

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