Endoform® Antimicrobial is an ovine extracellular matrix (ECM) plus 0.3% ionic silver, for acute and chronic wounds. Becomes incorporated into the wound and provides a porous scaffold for cell infiltration to build new tissue.
• Provides broad-spectrum antimicrobial activity for up to seven days and prevents biofilm formation
• Provides broad-spectrum protease modulation
• Indicates wound protease levels to optimize re-application rate
• Provides an intact extracellular matrix with an intact scaffold and 148 secondary molecules to help build new tissue
• Accessible to patients and clinicians from day one
Endoform® Antimicrobial is indicated for the management of acute and chronic wounds including partial- and full-thickness wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunneled/undermined wounds, surgical wounds (donor sites, grafts, post-Mohs surgery, post-laser surgery, podiatric and wound dehiscence), traumatic wounds (abrasions, lacerations, first- and second-degree burns and skin tears) and draining wounds.
15°C-40°C (59°F-104°F). Store in a clean and dry area. Endoform® Antimicrobial, like other silver-containing products, may darken upon storage, after hydration in saline, when exposed to light or when in contact with body fluids and tissues. This darkening does not affect product performance.
0.3% ionic silver
|Absorptive dressing format|
|Alginate dressing format|
|Antimicrobial effects up to 48 hours|
|Antimicrobial effects up to 3 days|
|Antimicrobial effects up to 7 days||●|
|Collagen dressing format||●|
|Composite dressing format|
|Contact layer dressing format|
|Foam dressing format|
|Gauze or non-woven dressing format|
|Gelling fiber dressing format|
|Hydrogel (amorphous) dressing format|
|Hydrogel (impregnated) dressing format|
|Hydrogel (sheet) dressing format|
|Impermeable to outside contaminants|
|Impregnated dressing format|
|Moisture vapor permeable|
|Secondary dressing required||●|
|Super absorbent polymers|
|Sustained release formula|
|Transparent film dressing format|
|Wound filler dressing format|
Moderate/Highly Exudating Wounds
Non/Minimally Exudating Wounds
Select a sheet of Endoform® Antimicrobial which is slightly larger than the wound and apply it aseptically. The sheet can be applied whole or trimmed to contact the wound margins. Multiple sheets can be used to cover the entire wound bed. For ease of handling, apply Endoform® Antimicrobial by placing the dry material in the wound and rehydrating with exudate or sterile saline until moistened. Ensure that Endoform® Antimicrobial conforms to the underlying wound bed. When rehydrated, Endoform® Antimicrobial transforms into a soft conforming sheet. To protect Endoform® Antimicrobial from adhering to the cover dressing, consider applying a non-adherent dressing over the top. Consider using Hydrofera Blue for a secondary dressing. The secondary dressing should be changed according to standard of care taking into account the level of exudate.
At the next dressing change, carefully cleanse the wound surface in accordance with established procedures. Endoform® Antimicrobial is naturally incorporated into the wound over time. At the next dressing change (three to seven days after) residual Endoform® Antimicrobial may or may not be observed depending on wound protease levels. If no residual Endoform® Antimicrobial is observed in the wound bed, consider increasing the amount applied to help modulate protease levels. If some residual Endoform® Antimicrobial is observed, this indicates that protease levels are balanced. Do not debride the residue as it contains extracellular matrix components that assist in wound healing. If the product has overlapped onto the periwound area, it may be gently removed around the edges if desired. Depending on the exudate color, residual Endoform® Antimicrobial may appear off-white to golden. Gently irrigate and re-apply at the same amount as the previous application or less. Change the cover dressing as needed, and when Endoform® Antimicrobial is re-applied.
Aroa Biosurgery manufactures medical products based on its proprietary extracellular matrix technology which enables health care professionals to repair soft tissue injuries.