Advanced treatment modalities: Wound care interventions that are typically applied when standard of care treatments have failed to lead to significant wound closure progress. Treatments include collagen products, cellular and/or tissue-based products, negative pressure wound therapy, hyperbaric oxygen therapy, and others.
Full-thickness wound: Tissue damage involving total loss of epidermis and dermis and extending, at the minimum, into the subcutaneous tissue and possibly through the fascia, muscle, or bone.
Granulation tissue: Tissue found in wounds beginning to heal. It is marked by pink or red tissue and may appear moist or shiny with an irregular or granular surface. Granulation tissue contains new vessels, tissue, fibroblasts, and inflammatory cells.