Skip to main content

OASIS® Wound Matrix

OASIS® Wound Matrix is a natural extracellular matrix derived from a single layer of porcine small intestinal submucosa (SIS) technology. The technology provides an intact three-dimensional extracellular matrix which allows for host cell migration. Storage at room temperature with a shelf-life of two years.

Smith+Nephew, Inc.

For over 150 years, Smith+Nephew has taken a pioneering approach to product design and services, helping to reduce the human and economic costs of wounds. *Trademark of Smith+Nephew
Toll free:(800) 876-1261 Fax:(817) 900-4100 Website:

• Proven management of a wide array of acute and chronic wounds
• Comes ready to apply
• Easy to trim to size and shape of wound
• Minimally processed and sterilized
• Can be used in a variety of settings, including long-term, outpatient, and at-home care
• Long-term storage without compromising ability to support healing
• Naturally derived structure that supports healing process
• Incorporated and absorbed into the wound
• Contains components similar to those found in the human dermis


OASIS® Wound Matrix is indicated for the management of wounds including partial- and full-thickness wounds, pressure injuries, venous ulcers, chronic vascular ulcers, tunneling and undermining wounds, diabetic ulcers, trauma wounds (abrasions, lacerations, second-degree burns, skin tears), draining wounds, and surgical wounds (donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric, wound dehiscence).


This device is derived from a porcine source and should not be used in patients with known sensitivity to porcine material. This device is not indicated for use on third-degree burns.

Warnings and Precautions

Do not re-sterilize. Discard all open and unused portions of OASIS® Wound Matrix.
Device is sterile if the package is dry, unopened, and undamaged. Do not use if the package seal is broken.
The device must be used prior to the expiration date.
Discard device if mishandling has caused possible damage or contamination.
OASIS® Wound Matrix should not be applied until excessive exudate, bleeding, acute swelling, and infection are controlled.

Adverse Effects/Reactions

The following complications are possible. If any of these conditions occur, the device should be removed:
Chronic inflammation (Initial application of wound dressings may be associated with transient, mild, localized inflammation.)
Allergic reaction
Excessive redness, pain, swelling or blistering

Storage Requirements

This device should be stored in a clean, dry location at room temperature.

How Supplied/Sizing
Fenestrated: 3cmx3.5cm, 3cmx7cm.
Product features
check_circle Assigned HCPCS code
cancel Minimally manipulated
check_circle Dehydrated
cancel Desiccated
cancel Flowable
cancel Micronized
check_circle Sheet form
cancel Requires refrigeration
cancel Shelf life greater than 2 years
cancel Shelf life limited
check_circle Indicated for acute wounds
check_circle Indicated for chronic wounds
check_circle Indicated for diabetic ulcers
check_circle Indicated for pressure ulcers
check_circle Indicated for second-degree burns
check_circle Indicated for surgical wounds
cancel Indicated for third-degree burns
check_circle Indicated for venous ulcers
cancel Contact manufacturer for usage guidelines
Other features
check_circle Educational Material Available
cancel Free Samples/Trials Available
check_circle Published Clinical Article Available
Recommended Use

Acute Wounds
Chronic Vascular Ulcers
Chronic Wounds
Dehisced Wounds
Diabetic Foot
Diabetic Ulcers
Draining Wounds
Granulating/Epithelializing Wounds
Partial- and Full-Thickness Wounds
Pressure Ulcers
Surgical Wounds (Donor Sites/Grafts, Post-Mohs Surgery, Post-Laser Surgery, Podiatric, Wound Dehiscence)
Tunneled or Undermined Wounds
Trauma Wounds (Abrasions, Lacerations, Second-Degree Burns, Skin Tears)
Venous Ulcers

Mode of Use/Application

Prepare the wound bed to make it free of exudate and devitalized tissue. Wait for any bleeding to stop before applying OASIS® Wound Matrix.
Measure the wound and select the appropriately sized sheet of dry OASIS® Wound Matrix. Cut the sheet to size and position it to cover the wound surface, extending slightly beyond all wound margins. If multiple sheets are necessary, overlap the edges slightly. As required, anchor OASIS® Wound Matrix using the physician's preferred fixation method.
Thoroughly rehydrate OASIS® Wound Matrix by applying sterile saline.
Apply a non-adherent primary wound dressing over OASIS® Wound Matrix.
Select an appropriate secondary dressing that will manage the wound exudate, keep the OASIS® Wound Matrix moist and keep all layers securely in place.
Only change the primary dressing as necessary, typically every 7 days, and change the secondary dressing as appropriate. Carefully remove any remaining loose product from around the wound edges as needed.

Removal & Change Frequency

To avoid product disruption, only change the primary dressing as necessary, typically every 7 days. If a gel forms on the wound surface, do not attempt to forcibly remove it. Gently rinse the wound surface, leaving the extracellular matrix (ECM) gel intact. Reapplication is typically necessary every 7 days. Reapply as needed if the OASIS® Wound Matrix is no longer covering the wound and wound is free of infection and necrosis, but not fully epithelialized.

Additional Recommended Dressings

Apply a non-adherent primary wound dressing over OASIS® Wound Matrix. Apply an appropriate secondary dressing (multilayer compression bandage system, total contact cast or other appropriate dressing) that will manage the wound exudate, keep the OASIS® Wound Matrix moist and keep all layers securely in place.


Porcine small intestinal submucosa that provides a single layer of fenestrated naturally derived ECM. OASIS® Wound Matrix is supplied sterile in peel-open packages and is intended for one-time use.

Clinically Tested


No posters match your selected filters. Remove some filtres, or reset them and start again.

Have a product to submit?

Be included in the most comprehensive wound care products directory
and online database.
Learn More