Despite modern precautions and protocols in place, surgical site infection (SSI) continues to be a risk. SSIs are the most common and costly of all hospital-acquired infections, with an estimated annual cost of $3.5 to $10 billion in the United States. Johns Hopkins Medicine reports that up to 3% of people who undergo a surgical procedure will develop an SSI. Additionally, SSIs can increase hospital length of stay by up to 9.7 days. Other complications of surgical wounds include osteomyelitis, gangrene, periwound dermatitis, periwound edema, wound dehiscence, and hematomas.