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OASIS® MICRO Micronized Wound Matrix

OASIS® MICRO Micronized Wound Matrix is an advanced wound care product comprised of micronized extracellular matrix (ECM) from porcine small intestinal submucosa used to manage wounds. It is a three-dimensional extracellular matrix that retains the natural composition of matrix molecules, provides a scaffold for cellular invasion and capillary growth and maintains and supports a healing environment for wound management.

Smith+Nephew, Inc.

For over 150 years, Smith+Nephew has taken a pioneering approach to product design and services, helping to reduce the human and economic costs of wounds. *Trademark of Smith+Nephew
Toll free:(800) 876-1261 Fax:(817) 900-4100 Website:

• Micronized formulation ensures the scaffold is in direct contact with the entire wound
• Stored at room temperature and simple to handle and manage with no advance preparation needed
• Contains components similar to those found in the human dermis
• Comes ready to apply
• Minimally processed and sterilized
• Long-term storage without compromising ability to support healing
• Naturally derived structure that supports healing process
• Incorporated and absorbed into the wound


OASIS® MICRO Micronized Wound Matrix is intended for the management of wounds including: partial- and full-thickness wounds, surgical wounds (donor sites/grafts, post-Mohs surgery, post-laser surgery, podiatric, wound dehiscence), trauma wounds (abrasions, lacerations, skin tears), tunneled or undermined wounds, second-degree burns, pressure injuries, venous ulcers, diabetic ulcers, chronic vascular ulcers, and draining wounds.


OASIS® MICRO Micronized Wound Matrix is derived from a porcine source and should not be used in patients with known sensitivity to porcine material. OASIS® MICRO is not indicated for use in third-degree burns.

Warnings and Precautions

OASIS® MICRO Micronized Wound Matrix is designed for single use only. Attempts to reprocess, re-sterilize and/or reuse may lead to failure and/or transmission of disease.
Discard all open and unused portions of OASIS® MICRO Micronized Wound Matrix.
OASIS® MICRO Micronized Wound Matrix is sterile if the pouch is dry, unopened, and undamaged. Do not use if the pouch seal is broken.
OASIS® MICRO Micronized Wound Matrix must be used prior to the expiration date.
Discard OASIS® MICRO Micronized Wound Matrix if mishandling has caused possible damage or contamination.
OASIS® MICRO Micronized Wound Matrix should not be applied until excessive exudate, bleeding, acute swelling and infection are controlled.

Adverse Effects/Reactions

The following complications are possible. Consider removing any residual product if any of these conditions occur:
Allergic reaction
Inflammation (Initial application of wound dressings may be associated with transient, mild, localized inflammation.)

Storage Requirements

This product should be stored in a clean, dry location at room temperature.

How Supplied/Sizing
200mg, 500mg, 1,000mg.
Product features
cancel Assigned HCPCS code
cancel Minimally manipulated
check_circle Dehydrated
cancel Desiccated
cancel Flowable
check_circle Micronized
cancel Sheet form
cancel Requires refrigeration
cancel Shelf life greater than 2 years
cancel Shelf life limited
check_circle Indicated for acute wounds
check_circle Indicated for chronic wounds
check_circle Indicated for diabetic ulcers
check_circle Indicated for pressure ulcers
check_circle Indicated for second-degree burns
check_circle Indicated for surgical wounds
cancel Indicated for third-degree burns
check_circle Indicated for venous ulcers
cancel Contact manufacturer for usage guidelines
Recommended Use

Acute Wounds
Cavity Wounds
Chronic Vascular Ulcers
Chronic Wounds
Deep Wounds
Dehisced Wounds
Diabetic Foot
Diabetic Ulcers
Granulating/ Epithelializing Wounds
Non/Minimally Exudating Wounds
Partial- and Full-Thickness Wounds
Pressure Ulcers
Surgical Wounds
Trauma Wounds
Tunneled or Undermined Wounds
Venous Ulcers

Mode of Use/Application

NOTE: Always handle OASIS® MICRO Micronized Wound Matrix using aseptic technique.
Prepare the wound bed using standard techniques. Apply OASIS® MICRO Micronized Wound Matrix by squeezing the bottle. The spout can be trimmed with scissors or the cap removed if a wider spout is preferred. Lightly cover as much of the wound as possible.
If needed, gently wet the application area with sterile saline to ensure OASIS® MICRO Micronized Wound Matrix is hydrated and adheres to the wound. Alternatively, a small amount of sterile saline can be mixed with the product in a sterile container to make a paste prior to application.
Apply a non-adherent dressing and secondary dressings.
Change secondary moisture-control dressings carefully as often as needed, but leave the non-adherent dressing in place until ready for re-application to prevent damage to the incorporating ECM.
Successful absorption may result in a caramel-colored gel. Do not remove the gel as it includes the incorporating ECM.

Removal & Change Frequency

If desired, re-apply OASIS® MICRO Micronized Wound Matrix as needed, typically every 3 to 7 days.

Additional Recommended Dressings

Apply a non-adherent primary wound dressing over OASIS® MICRO Micronized Wound Matrix. Assess the wound to determine moisture conditions and apply appropriate secondary dressing to maintain a moist wound environment.


Porcine small intestinal submucosa micronized product that comes in a squeeze bottle for ease of use.

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