TriCoreMatrix is a cutting-edge, sterile, minimally manipulated, dehydrated allograft designed to support homologous use in clinical applications. It is meticulously derived from human placental membranes, specifically the amnion, intermediate layer, and chorion, obtained from healthy, consenting donors. The allograft incorporates a basement membrane and a stromal matrix collagen layer, providing structural integrity and biological compatibility for therapeutic purposes. It provides a natural scaffold that helps maintain a protective environment for the tissue surface. Its biocompatible properties make it ideal for use in managing acute and chronic wounds, surgical procedures, and other clinician-directed applications where a protective covering or barrier is desired.
Cellution Biologics is a regenerative medicine company specializing in advanced human tissue–based allografts for surgical, wound care, and specialty clinical applications. With a focus on scientific rigor, innovation, and quality, Cellution Biologics Inc. partners with clinicians to deliver solutions that enhance healing while supporting operational excellence across diverse care settings.
• Biologic Scaffold Supporting Natural Healing: retains key growth factors to support tissue repair and epithelialization.
• Broad Wound Applicability: Chronic ulcers (diabetic, pressure, venous), surgical and reconstructive wounds, traumatic wounds (burns, abrasions, lacerations)
• Ambient Storage & Long Shelf-Life
• Easy to Use: ready-to-apply at point of care
• Compatible With Adjunct Therapies: Can be used alongside standard wound care protocols including NPWT and hyperbaric oxygen therapy as part of comprehensive treatment plans.
TriCoreMatrix is restricted to homologous use. It acts as a barrier and provide a protective coverage from the surrounding environment for acute and chronic wounds such as partial and full thickness wounds, pressure sores/ulcers, venous ulcers, diabetic ulcers, chronic vascular ulcers, tunneled/undermined wounds, surgical wounds (eg, donor site/grafts, post-laser surgery, post–Mohs surgery, podiatric wounds, wound dehiscence), trauma wounds (eg, abrasions, lacerations, partial thickness burns, skin tears), and draining wounds.
TriCoreMatrix should not be used with known hypersensitivity to ofloxacin, vancomycin, and amphotericin B. It should not be used on:
1. Areas with active or latent infection and/or
2. A patient with a disorder that would create an unacceptable risk of postoperative complications.
1. Do not re-sterilize, keep away from sunlight, do not use if package is damaged and consult instructions for use, Keep dry, keep out of reach of children. Do not re-use. Contains biological material of human origin.
2. Caution should be used when treating patients with a known sensitivity to ofloxacin, vancomycin, and amphotericin antibiotics. Expert opinion is required before use on babies and pregnant women.
3. The graft is intended for single-patient use only.
4. Strict donor screening and laboratory testing, along with dedicated processing and sterilization methods are employed to reduce the risk of any disease transmission. However, as with all biological implants, an absolute guarantee of tissue safety is not possible. As with any allograft, complications at the graft site may occur post operatively that are not readily apparent. These include, but are not limited to the transmission of communicable diseases, including those of unknown etiology, transmission of infectious agents such as viruses, bacteria and fungi, immune rejection of, or allergic reaction to, implanted HCT/Ps.
5. Discard all damaged, mishandled or potentially contaminated tissue.
6. This product has not been tested in combination with other products.
7. TriCoreMatrix shall not be ordered, distributed or dispensed for veterinary use.
As with any procedure the possibility of infection exists. Proprietary processing and validated sterilization methods are employed to eliminate potential deleterious components of the allograft. However, with biological implants, the possibility of rejection still exists. Complaints or adverse events, including the suspected transmission of diseases attributable to this allograft, should be reported immediately. Please contact your local sales representative, authorized distributor, or at customerservice@cellutionbiologics.com for information on returns. All products being returned must be in original unopened container, packaging, original label and in resalable condition.
Store in a clean and dry environment at ambient temperature between 15°C–30°C. DO NOT FREEZE. The distributor, intermediary and/or end-user clinician or facility is responsible for storing product under appropriate conditions prior to further distribution or implantation.
TriCoreMatrix retains the inherent collagens, growth factors, and proteins of the native tissue.
SKU GTIN Dimension
TCM0014 8906158202117 14mm disc
TCM0018 8906158202124 18mm disc
TCM0202 8906158202131 2cm x 2cm
TCM0203 8906158202148 2cm x 3cm
TCM0204 8906158202155 2cm x 4cm
TCM0303 8906158202162 3cm x 3cm
TCM0305 8906158202179 3cm x 5cm
TCM0404 8906158202186 4cm x 4cm
TCM0406 8906158202193 4cm x 6cm
TCM0407 8906158202209 4cm x 7cm
TCM0408 8906158202216 4cm x 8cm
TCM0505 8906158202223 5cm x 5cm
TCM0608 8906158202230 6cm x 8cm
TCM0612 8906158202247 6cm x 12cm
TCM0707 8906158202254 7cm x 7 cm
TCM1010 8906158202261 10cm x 10cm
TCM1020 8906158202278 10cm x 20cm
TCM2020 8906158202285 20cm x 20cm
Acute Wounds
Burns
Chronic Wounds
Dehisced Wounds
Diabetic Foot
Infected Wounds
Moderate/Highly Exudating Wounds
Non/Minimally Exudating Wounds
Pressure Ulcers
Surgical Wounds
Venous Ulcers
Step 1: Remove the allograft from the outer packaging.
Step 2: Inspect the pouch packaging. DO NOT USE if the packaging is damaged, if elements are missing or appear to have been tampered with, if the labeling is illegible, or if the expiration date occurs in the past.
Step 3: Utilizing aseptic technique, peel open the outer pouch and place the inner pouch to the sterile
field.
Step 4: Wait to open the inner pouch until ready to place the graft. Locate the tear notch on the pouch, and tear open.
Step 5: Using sterile non-toothed forceps, remove the graft and place it directly at the surgical or wound site. Allograft can be trimmed with a sterile sharp scissor in its dry state if there is a requirement.
Step 6: Apply TriCoreMatrix on the wound gently with sterile forceps and spread the membrane to maximize the contact with the wound surface. If needed, prior to application, the membrane can be hydrated with sterile saline solution. When necessary secure using the physician’s choice of fixation.
Note: Allografts are human tissue products and appearance may vary between donors. Variations in
color, opacity, and thickness are normal due to the nature of human tissue.
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