Hydrogel wound dressing sheets are three-dimensional networks of cross-linked hydrophilic polymers that are insoluble in water and interact with aqueous solutions by swelling. These dressings help maintain a moist wound healing environment, promote granulation and epithelialization, and facilitate autolytic debridement. Because of the high water content of hydrogels, they typically cannot absorb large amounts of exudate. Hydrogel dressings are also available in amorphous form and impregnated in gauzes or nonwoven sponges.