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Collagen wound dressings are gels, pads, particles, pastes, powders, sheets, or solutions derived from bovine, equine, porcine, or avian sources. Some may interact with wound exudate to form a gel. Indicated for partial- and full-thickness pressure injuries, venous ulcers, donor sites, surgical wounds, vascular ulcers, diabetic ulcers, second-degree burns, abrasions, and traumatic wounds. Usually require a secondary dressing.

Collagen dressings are sheets, pads, particle and gels derived from bovine, equine, porcine or avian sources. These dressings encourage the deposition and organization of newly formed collagen fibers and granulation tissue in the wound bed.

Collagen dressings feature the following general performance properties and attributes:
• Absorbent
• Maintain moist wound healing environment
• May be used with topical agents
• Conformable
• Nonadherent
• Easy to apply and remove

Collagen dressings are indicated for use as a primary dressing in the treatment of partial- and full-thickness wounds such as skin grafts, donor sites, surgical wounds, tunneling wounds, infected and non-infected wounds and wounds with minimal to heavy exudate (depending on the form of the dressing).

Collagen dressings are generally contraindicated for dry wounds and third-degree (full-thickness) burns, and in patients with sensitivities to collagen or bovine products.

The following general warnings apply to collagen-based dressings. Always refer to manufacturer information for Warnings and Precautions for a specific product.

Require a secondary dressing.
Not recommended for necrotic wounds.
May require rehydration on removal.



BIOPAD™ is a primary dressing composed of 100% native equine type I collagen that can accelerate the closure of hard-to-heal wounds.

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Cutimed® Epiona

Cutimed® Epiona® is an innovative 3D matrix wound dressing, which is made from 90% native bovine collagen with 10% calcium-sodium alginate. Mimics the function of a healthy dermis and boosts the wound healing process.

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Endoform™ Natural

Endoform™ Natural is an advanced extracellular matrix (ECM) for acute and chronic wounds. Incorporates into the wound and provides a porous bioscaffold for rapid cell infiltration to build new tissue.

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HYCOL® Hydrolyzed Collagen Powder

HYCOL® Hydrolyzed Collagen Powder is type I bovine hydrolyzed collagen and contains no additives.

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3M™ Fibracol™ Plus Collagen Wound Dressing with Alginate

3M™ Fibracol™ Plus Collagen Wound Dressing with Alginate combines the structural support of collagen with the exudate management of alginate. 90% collagen and 10% alginate.

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3M™ Promogran™ Collagen Matrix with ORC

3M™ Promogran™ Collagen Matrix with ORC is comprised of 45% oxidized regenerated cellulose (ORC) and 55% collagen in a sterile, freeze-dried composite.

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BIOCOL™ is a bovine collagen powder which interacts with the wound to form a gel that provides a moist wound healing environment, reduces inflammation, and promotes cellular regeneration.

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BIOSTEP* Collagen Matrix

BIOSTEP* Collagen Matrix targets and deactivates excess MMPs to optimize wound closure for chronic wounds. Highly conformable and easy to apply.

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ColActive® Plus Collagen Sheets and Powder

ColActive® Plus Collagen Sheets and Powder feature EDTA and fish-derived collagen that target and deactivate elevated MMP activity as well as alginate and CMC that allow the dressing to absorb wound drainage while still maintaining an optimal moisture balance for wound closure.

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Collatek® Collagen Gel

Collatek® Collagen Gel is 100% non-hydrolyzed type 1 bovine native collagen. Proprietary Kollagen™ technology process protects and retains significantly more native triple helical protein structure, thus allowing superior stability of the molecule and scaffolding through all four phases of wound healing.

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