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Collagens

Collagen wound dressings come in many forms and are derived from bovine, equine, ovine, porcine, or avian sources. Some may interact with wound exudate to form a gel. Collagens are indicated for partial- and full-thickness pressure injuries, venous ulcers, donor sites, surgical wounds, vascular ulcers, diabetic ulcers, second-degree burns, abrasions, and traumatic wounds. Collagens usually require a secondary dressing.

Collagen dressings are sheets, pads, particle and gels derived from bovine, equine, porcine or avian sources. These dressings encourage the deposition and organization of newly formed collagen fibers and granulation tissue in the wound bed.

Collagen dressings feature the following general performance properties and attributes:
• Absorbent
• Maintain moist wound healing environment
• May be used with topical agents
• Conformable
• Nonadherent
• Easy to apply and remove

Collagen dressings are indicated for use as a primary dressing in the treatment of partial- and full-thickness wounds such as skin grafts, donor sites, surgical wounds, tunneling wounds, infected and non-infected wounds and wounds with minimal to heavy exudate (depending on the form of the dressing).

Collagen dressings are generally contraindicated for dry wounds and third-degree (full-thickness) burns, and in patients with sensitivities to collagen or bovine products.

The following general warnings apply to collagen-based dressings. Always refer to manufacturer information for Warnings and Precautions for a specific product.

Require a secondary dressing.
Not recommended for necrotic wounds.
May require rehydration on removal.

Products

3M™ Promogran Prisma™ Collagen Matrix with ORC and Silver

3M Promogran Prisma Collagen Matrix with ORC and Silver is comprised of a sterile freeze-dried composite of 44% oxidized regenerated cellulose (ORC), 55% collagen and 1% silver—ORC with 25% w/w ionically bound silver (0.017 mg/sq cm total silver).

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BIOPAD™

BIOPAD™ is a primary dressing composed of 100% native equine type I collagen that can accelerate the closure of hard-to-heal wounds.

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Cutimed® Epiona

Cutimed® Epiona® is an innovative 3D matrix wound dressing, which is made from 90% native bovine collagen with 10% calcium-sodium alginate. Mimics the function of a healthy dermis and boosts the wound healing process.

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Endoform™ Natural

Endoform Natural offers versatile use in acute and chronic wounds. It is simple to use, can be applied by any wound care professional, and provides structure and biology to helps advance stalled wounds to closure.

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3M™ Fibracol™ Plus Collagen Wound Dressing with Alginate

3M Fibracol Plus Collagen Wound Dressing with Alginate combines the structural support of collagen with the exudate management of alginate. 90% collagen and 10% alginate.

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3M™ Promogran™ Collagen Matrix with ORC

3M™ Promogran™ Collagen Matrix with ORC is comprised of 45% oxidized regenerated cellulose (ORC) and 55% collagen in a sterile, freeze-dried composite.

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BIOCOL™

BIOCOL™ is a bovine collagen powder which interacts with the wound to form a gel that provides a moist wound healing environment, reduces inflammation, and promotes cellular regeneration.

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BIOSTEP* Collagen Matrix

BIOSTEP* Collagen Matrix targets and deactivates excess MMPs to optimize wound closure for chronic wounds. Highly conformable and easy to apply.

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ColActive® Plus Collagen Sheets

ColActive® PLUS Ag Collagen Sheets feature fish-derived Collagen, EDTA, Alginate, CMC, and silver that allow the dressing to absorb wound exudate and maintain an optimal moisture balance for wound closure.

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CollaSorb

CollaSorb is made from 100% non-hydrolyzed type 1 bovine native collagen. It transforms into a soft gel when in contact with wound exudate.

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