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BIOSTEP* Collagen Matrix

BIOSTEP* Collagen Matrix targets and deactivates excess MMPs to optimize wound closure for chronic wounds. Highly conformable and easy to apply.

Smith+Nephew, Inc.

For over 150 years, Smith+Nephew has taken a pioneering approach to product design and services, helping to reduce the human and economic costs of wounds. *Trademark of Smith+Nephew
Toll free:(800) 876-1261 Fax:(817) 900-4100 Website:

• Unique dual-action MMP targeting and deactivation
• Absorbs a high level of moisture
• Patient-friendly
• Easy to use


BIOSTEP* is indicated for management of full- and partial-thickness wounds including: pressure injuries, diabetic ulcers, ulcers caused by mixed vascular etiologies, venous ulcers, donor and graft sites, abrasions, traumatic wounds healing by secondary intention, dehisced surgical wounds, and first- and second-degree burns.


BIOSTEP* Collagen Matrix Dressing should not be used on patients with a known allergy or sensitivity to porcine collagen, any other ingredient or on third-degree burns.

Warnings and Precautions

If sensitivity to BIOSTEP* develops, discontinue use. BIOSTEP* dressings may be used under compression therapy under the supervision of a health care professional.

United States federal law restricts this device to sale by or on the order of a physician.

How Supplied/Sizing
2"x2", 4"x4".
Product features
cancel Antimicrobial format available
cancel Compatible w/ topicals
check_circle Conforms readily to wound
check_circle Cuttable
check_circle Flexible
check_circle Gels on contact w/ exudate
cancel Limited shelf life
cancel Moldable
cancel Powder
cancel Rope
check_circle Secondary dressing required
cancel Silicone-based adhesive
check_circle Usable on infected wounds
check_circle Variety of sizes
Other features
check_circle Educational Material Available
check_circle Free Samples/Trials Available
cancel Published Clinical Article Available
Recommended Use

Diabetic Ulcers
Donor Sites
First- and Secondary-Degree Burns
Pressure Ulcers
Surgical Wounds
Traumatic Wounds
Venous Ulcers

Mode of Use/Application

Prior to application, the wound bed should be debrided and then irrigated with an appropriate wound cleanser or water.

The dressing should be cut to fit the wound size exactly. For heavily exudating wounds, the dressing should be applied directly to the wound bed. For dry wounds with minimal exudate, the wound bed should be moistened with water to begin the gelling process.

Removal & Change Frequency

Remove secondary dressing with care. Gently remove BIOSTEP* Collagen Matrix Dressing, ensuring that the dressing removal does not damage delicate newly-formed tissues.
Dressings may be left in place for up to 6 days depending on the level of exudate or as good nursing practice dictates.

Additional Recommended Dressings

BIOSTEP* should be covered with a suitable secondary dressing.

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